American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant SurgeonsJournal Article
18 Nov 2024
Pediatric donors are underutilized for simultaneous pancreas-kidney transplantation (SPK) due to concern about technical complications and inadequate islet and/or renal mass. We analyzed our experience with simultaneous en-bloc kidney and pancreas transplantation (SEBKP) using pediatric donors on eight consecutive adult patients from 1997-2018. En-bloc kidney transplants were implanted intraperitoneally and contralaterally to right-sided pancreas grafts. All patients became insulin independent immediately; with one case of delayed kidney function and one case of insulin resistance; there were no graft thromboses. Donor age averaged 5.0±1.7 years and weight 19.8±4.8kg; recipients averaged 46.6±12.8 years and BMI 25.2±3.8kg/m. Postoperative creatinine, glucose and c-peptide reflected good graft function. SEBKP transplantation is a safe technique providing excellent long-term glycemic control and kidney function to adult recipients.
Declaration of Competing Interest ☒ The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: JSO is an Associate Editor of the American Journal of Transplantation If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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