Journal of the American Academy of DermatologyReview
undefined Apr 2025
The second part of this CME article discusses sunscreen regulation and safety considerations for humans and the environment. First, we provide an overview of the history of the US Food and Drug Administration's regulation of sunscreen.
Recent Food and Drug Administration studies clearly demonstrate that organic ultraviolet filters are systemically absorbed during routine sunscreen use, but to date there is no evidence of associated negative health effects.
We also review the current evidence of sunscreen's association with vitamin D levels and frontal fibrosing alopecia, and recent concerns regarding benzene contamination. Finally, we review the possible environmental effects of ultraviolet filters, particularly coral bleaching.
While climate change has been shown to be the primary driver of coral bleaching, laboratory-based studies suggest that organic ultraviolet filters represent an additional contributing factor, which led several localities to ban certain organic filters.
Conflicts of interest Dr DeLeo has served as a consultant for Estée-Lauder. Dr Adler has served as a research investigator and/or consultant to AbbVie, Dermavant, and Skin Research Institute, LLC. Drs Azim, Bainvoll, and Vecerek have no conflict of interest to declare.
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