Journal of the American Academy of DermatologyReview
undefined Dec 2024
In this CME, we review 2 specific categories of ulcers: inflammatory (where inflammation is the primary pathologic process leading to ulceration) and vaso-occlusive (where occlusion is the primary process).
Inflammatory ulcers include pyoderma gangrenosum and vasculitides, whereas livedoid vasculopathy, calciphylaxis, and Martorell ulcers are vaso-occlusive ulcers. Determining the causes of ulcers in these conditions may require laboratory evaluation, biopsy, and imaging.
Conflicts of interest Dr Fett is on the board of the Medical Dermatology Society and serves as the education cochair for the MDS. Dr Fett is an author and editor for UpToDate vasculitis, lichen sclerosus, and pyoderma gangrenosum topics. Dr Alavi serves as the board member of HS foundation and as principal investigator for BI (Boehringer Ingelheim) and Processa and consultant for Abbvie, BI, InflaRx, Novartis, UCB. Dr Ortega is the current President of the Pacific Dermatology Association and serves as an associate editor for Dermatology (Karger). Additionally, he is a consultant for Genentech and Guidepoint and an advisor to Bristol Meyer Squibb, Boehringer Ingelheim and Janssen. Dr Ortega has received research grants from the Lilly, Janssen, Incyte and Pfizer. He is supported by NIH NIAMS R01 AR083110. The other authors have no conflicts of interests to disclose.
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